Prevalence of disability in Australian elderly: Impact of trends in obesity and diabetes
Introduction
Obesity and diabetes, two known predictors of disability (Wong et al., 2015), have increased in prevalence over the last three decades with obesity increasing more rapidly amongst the younger adult population (Gordon-Larsen et al., 2010, Ogden et al., 2006). These trends pose a challenge to an ageing population. Significant lifestyle predictors in mid-life for disability in old age include obesity, diabetes, smoking and hypertension (Wong et al., 2015). Whilst there have been improvements in smoking prevalence and better management of hypertension over time, based on trends in the first decade in the 21st century in the United States of America and Australia, obesity has been projected to increase between 34% and 43% in adults (Huffman et al., 2012, Walls et al., 2012, Magliano et al., 2008) by 2020–2025. Diabetes and glucose intolerance have also been projected to increase rapidly over the same time period (Magliano et al., 2008).
Recent trends of disability in the United States have shown an increase in disability amongst those aged 40–64 years and 55–64 years (Hung et al., 2011, Martin and Schoeni, 2014, Freedman et al., 2013). It is likely that this will impact on the population's productivity, pension schemes, health and aged care resources. Similar trends, measured as quality adjusted life expectancy, years lived with disability or compression of morbidity, have been demonstrated in both middle-aged adults as well as those aged over 65 years (Wen and O'Rance, 2008, Crimmins and Beltrán-Sánchez, 2011, Van Baal et al., 2006, Stewart et al., 2009). The recently updated Global Burden of Disease Study reported a shift in the burden of disease from premature death to years lived with disability (Murray et al., 2012). Projection studies for disability adjusted life expectancy and compression of morbidity over the next decade have concluded that even with declining smoking trends, the impact of obesity will lead to increased years lived with disability or compression of morbidities(Van Baal et al., 2006, Stewart et al., 2009). If current obesity trends continue, we can anticipate a rise in onset of new disability as our population ages. This has important implications with regard to those around retirement age in terms of their ability to prolong their productive years and continuing to live independently. To date, whilst there has been an analysis of the impact of obesity and smoking trends on life expectancy, little is known of the future impact of mid-life obesity and diabetes on the prevalence of disability. Disability, particularly in terms of limitations to activities of daily living (ADL), is an important general health measure as it relates to loss of independent living with early onset resulting in early retirement and disability pensions (Burdorf et al., 2014).
We aimed to estimate the likelihood of surviving free of disability up to age 75 years in Australia based on mid-life obesity and diabetes prevalence. We modelled the contemporary population using longitudinal data from the Australian Lifestyle, Obesity and Diabetes study (AusDiab) and estimated changes in disability prevalence associated with future (2025) and past (1980) midlife obesity and diabetes levels.
Section snippets
Study population
The Australian Diabetes, Obesity and Lifestyle study (AusDiab) commenced in 1999/2000 and involved 11,247 adults aged 25 years and over, from 42 randomly selected clusters across Australia. In brief, demographic and medical information were collected by questionnaire, and blood pressure and anthropometrics were measured. Blood tests included a 75 g oral glucose tolerance test and fasting blood samples were collected. The baseline questionnaire included the SF-36 (Ware & Sherbourne, 1992), where
Results
Of the 2107 study participants, 154 developed new disability and 257 died in the 12 years between the baseline and the follow-up. Compared to those who survived free of disability, those who developed disability were more likely to be women, older, current smokers, have obesity, diabetes and hypertension (Table 1).
Risk factors significantly associated with new disability when adjusted only for age and sex were current smoking, obesity, diabetes, hypertension, HDL cholesterol and triglycerides.
Discussion
We have estimated, for the first time, the likely prevalence of disability amongst those aged 55–74 years in Australia, 10 years after the baseline Ausdiab study (2000), and compared to the likely prevalence of disability if the year 2000 prevalence of obesity and diabetes had resembled the levels observed in the year 1980 or the estimates projected for the year 2025. We estimated that if obesity and diabetes prevalence were as in 1980, it would have contributed to 14.3% (range 13.6%–17.0%) less
Conclusion
The increase in obesity and diabetes prevalence between the years 1980 and 2000 is estimated to have contributed to 14% of potentially avoidable disability in Australians aged between 55 and 74 years in 2010. If obesity and diabetes trends continue to previously predicted levels by 2025, we estimate that they will lead to a further 13% increase disability prevalence. This has implications particularly for our working and ageing population.
The following are the supplementary data related to this
Authors' contributions
EW—formulation of research question, design of protocol, data analysis, drafted manuscript and responsible for manuscript submission and responding to reviewer comments; AP—formulation of research question, design of protocol, and interpretation and commented on manuscript drafts; MW—interpretation and commented on manuscript drafts. CS, KB, and DS—commented on manuscript drafts. EW and AP had full access to all of the data in the study and take responsibility for the integrity of the data and
Funding
This work is supported by funding from the Australian Research Council [Linkage Project Grant 12010041 & Discovery Grant120103277], NHMRC Project Grant [1027215] and, in part, by the Victorian Government's Operational Infrastructure Support (OIS) Program. EW is supported by Monash University Australian Postgraduate Award and Baker IDI Bright Sparks Foundation Top–up Award, AP is supported by a VicHealth and National Health and Medical Research Council (NHMRC) fellowship. KB is supported by a
Conflict of interest
The authors declare that there are no conflicts of interests.
Transparency Document
Acknowledgments
We wish to thank the AusDiab Steering Committee for providing data from the AusDiab study. We wish to thank the AusDiab study participants.
References (28)
The magnitude of association between overweight and obesity and the risk of diabetes: a meta-analysis of prospective cohort studies
Diabetes Res. Clin. Pract.
(2010)- et al.
Socioeconomic status and weight change in adults: a review
Soc. Sci. Med.
(2005) Prevention of chronic disease in the 21st century: elimination of the leading preventable causes of premature death and disability in the USA
Lancet
(2014)Years of life lost and healthy life-years lost from diabetes and cardiovascular disease in overweight and obese people: a modelling study
Lancet Diabet. Endocrinol.
(2015)- et al.
Trends in disability and related chronic conditions among the forty-and-over population: 1997–2010
Disabil. Health J.
(2014) Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010
Lancet
(2012)Diabetes and risk of physical disability in adults: a systematic review and meta-analysis
Lancet Diabet. Endocrinol.
(2013)- et al.
The importance of preventing work-related disability
Scand. J. Work Environ. Health
(2014) - et al.
Mortality and morbidity trends: is there compression of morbidity?
J. Gerontol. Ser. B Psychol. Sci. Soc. Sci.
(2011) Adjustable gastric banding and conventional therapy for type 2 diabetes: a randomized controlled trial
JAMA
(2008)