ReviewAssociation of Analgesic Block With the Incidence of Complications Following Hypospadias Surgery; A Meta-Analysis
Section snippets
Search Strategies
The protocol of this review was registered prospectively with the PROSPERO registry (#CRD42020220327). The study was preformed according to the Cochrane collaboration recommendations and complies with the Preferred Reporting Items for Systematic Reviews and Meta Analyses statement (PRISMA). The PROSPERO registry was updated on June 13, 2021 to indicate completion of the analysis as well as to denote that a minimum of 6 months postoperative follow-up was required for inclusion (accidently
RESULTS
The database search yielded 350 records (Fig. 1). After removal of duplicated records, 178 studies were screened from which 28 full text articles were assessed for eligibility. Of those 28 studies, 17 studies met our qualitative criteria for examination and 10 studies within this group met predetermined criteria for quantitative examination and meta-analysis Figure 1, PRISMA flow diagram, details the study selection process (Fig. 1).
A total of 3201 patients from 10 studies met study inclusion
DISCUSSION
Debate as to the impact of caudal blocks on outcomes following hypospadias correction in children exists. Some physicians have speculated that caudal blocks cause penile engorgement and the resulting tissue edema delays wound healing. However, a definitive biologic mechanism for why caudal blocks may be associated with worse outcomes has never been demonstrated.5,22 While the previous meta-analysis published by Tanesco et al. in 2019 identified an increase in postsurgical complications for
REGISTRY
PROSPERO #CRD42020220327
AUTHORS CONTRIBUTION
Dr. Adler conceptualized and designed the study, drafted the initial manuscript, and reviewed and revised the manuscript and was responsible for meta-analysis registry. Dr. Bhatia designed the study, drafted the initial manuscript, and reviewed and revised the manuscript. Dr. Chandrakantan designed the study, drafted the initial manuscript, and reviewed and revised the manuscript. Dr. Nathanson conducted statistical analysis for the manuscript, and reviewed and revised the manuscript. Ms.
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Modified PATIO technique for urethrocutaneous fistula after hypospadias repair: Experience from a tertiary referral hospital
2024, Journal of Pediatric UrologyImpact of caudal block on revision rates after hypospadias repair: Multi-institution review
2023, Journal of Pediatric UrologyPendulum swings again in favour of caudal block for hypospadias
2023, Journal of Pediatric UrologyEfficacy of adjuvant dexmedetomidine on penile block for pediatric hypospadias repair
2023, Journal of Pediatric Urology
Drs Adler and Bhatia have contributed equally to constitute first authorship.
Disclosure: Dr. Austin is a consultant to Allergan and Urovant. The remaining authors have no conflicts of interest to disclose.
Funding Support: No funding was secured for this study.