Advances in liver transplantationDonation: Donor evaluationImportance of Awareness of Perioperative Social and Physical Situations of Living Donors for Liver Transplantation
Section snippets
Patient and Methods
Perioperative qualities of life after living donation for liver transplantation were assessed with questionnaires including the Medical Outcomes Study 36-Item Short-Form Health Survey version 2 (SF36-v2).3, 4 Preoperative psychological assessment was done by a psychiatrist, who analyzed Hamilton's depression and anxiety scores. Nonparametric Mann-Whitney tests were used to determine statistical significance with P values <.05 considered to be significant.
Results
The 31 among 33 living donors who answered questionnaires (93.9%) included 15 males and 16 females of average age of 39.7 years (Table 1). Median hospital stay was 16 days. Median duration after donor surgery was 78 months. Ten of 33 (35.7%) donors considered themselves to be the only donor. The decision to be a donor was made prior to informed consent in 23 donors (74.1%). Six months was needed for them to experience full recovery after donor surgery. The Hamilton depression/anxiety score
Discussion
Living donors are widely accepted for liver transplantation. However, donor hepatectomy is not always safe not only for physical status but also for mental health. A study from a high-volume hepatobiliary center reported an 47.3% overall morbidity rate among right lobe donations, which did not significantly improve with time. Also, some disfiguring complications, which were graded as minor, may have significantly impacted donor QOL.5 Moreover, the estimated donor death rate has been reported to
References (13)
- et al.
Translation, adaptation, and validation of the SF-36 Health Survey for use in Japan
J Cli Epidemiol
(1998) - et al.
Short- and long-term donor morbidity in right lobe living donor liver transplantation: 91 consecutive cases in a European Center
Am J Transplant
(2011) Liver transplantation in Japan-registry by the Japanese Liver Transplantation Society
Jpn J Transplant
(2010)- et al.
Quality of life after lobectomy for adult liver transplantation
Transplantation
(2002) - et al.
The MOS 36-Item Short-Form Health Survey (SF-36): IIPsychometric and clinical tests of validity in measuring physical and mental health constructs
Medical Care
(1993) - et al.
Documented deaths of hepatic lobe donors for living donor liver transplantation
Liver Transpl
(2006)
Cited by (8)
Anxiety, pain intensity, and decision regret of living liver donors during postoperative period
2023, Applied Nursing ResearchCitation Excerpt :Acute pain was the most commonly reported symptom by living liver donors after surgery (Thuluvath et al., 2021). Acute pain would impact the recovery of daily activity and quality of life if it was not managed suitably in the postoperative period (Holtzman et al., 2014; Narumi et al., 2012). Acute pain intensity within the first three postoperative days was moderate to severe, especially when donors got out of bed and at other times of mobility (Chen et al., 2010; Holtzman et al., 2014; Khan et al., 2015; Lee et al., 2012).
Psychosocial Assessment of Donors in Pediatric Living Donor Liver Transplantation: A Systematic Review
2021, Transplantation ProceedingsCitation Excerpt :Kimura et al [5] showed in their study that 4.2% of donors developed psychiatric complications after surgery. Two studies found that donors experienced depression and anxiety after surgery and that there should be focus on their mental health [35,40]. A research team in Turkey indicated that psychological disturbance is frequently observed [38].
Mental health assessment of altruistic non-directed kidney donors: An EAPM consensus statement
2018, Journal of Psychosomatic ResearchCitation Excerpt :A large study of 2455 kidney donors identified several post donation factors that increased the risk for depression: longer recovery time, greater financial burden and feeling morally obligated to donate [11]. Considering themselves the only option for an organ for a specific patient correlated with depression and anxiety, while not having enough time to think prior correlated with lower social function post donation [20]. Open donor nephrectomy (as opposed to laparoscopic intervention) correlated with lower mental health scores [21].
Transitional Study of Patient-Controlled Analgesia Morphine with Ketorolac to Patient-Controlled Analgesia Morphine with Parecoxib among Donors in Adult Living Donor Liver Transplantation: A Single-Center Experience
2016, Transplantation ProceedingsCitation Excerpt :Holtzman et al [3], from their recent comprehensive study on acute and chronic post-surgical pain after living liver donation, showed that as high as 42% of donors had moderate to severe pain at rest with current standard pain-controlled modalities. Severe post-surgical wound pain can be detrimental physically and psychologically to the recovery of the donor [3,10]. Poorly controlled acute post-surgical pain can also lead to development of chronic pain [3,11].
The life experiences of living liver donors: A qualitative meta-synthesis
2022, Research in Nursing and HealthA qualitative study on psychological experience of pediatric living donor liver transplantation donors
2019, Chinese Journal of Practical Nursing