Letter to the Editors-in-ChiefLupus Anticoagulant (LAC) testing in patients with inflammatory status: Does C-reactive protein interfere with LAC test results?
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2021, Thrombosis ResearchCitation Excerpt :Many assays for detecting LA are sensitive to CRP; this interferes with the results and results in false positives [21]. CRP is an acute phase protein with known affinity for APA [24,25,26]. In our study, although CRP levels were higher in LA-positive patients (p < 0.001) this variable did not emerge as a prognostic factor of mortality in the multivariate model.
False positive lupus anticoagulant tests in patients with high C-reactive protein: A comparison of two hexagonal phase reagents
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