Elsevier

Stem Cell Research

Volume 53, May 2021, 102269
Stem Cell Research

Lab Resource: Multiple Cell Lines
Generation of integration-free induced pluripotent stem cells from healthy individuals

https://doi.org/10.1016/j.scr.2021.102269Get rights and content
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Abstract

Ten human induced pluripotent stem cell (iPSC) lines have been derived from five healthy controls matched to a study including Attention-Deficit Hyperactivity Disorder patients (ADHD). Both female and male children and adolescents aged 6–18 years were recruited. Isolated keratinocyte cells from the participants were reprogrammed into iPSCs using non-integrating Sendai virus to deliver the reprogramming factors Oct3/4, Sox2, Klf4 and cMyc.

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Both authors contributed equally.