Letter to the EditorAmelioration of anergia and thought disorder with adjunctive high frequency cerebellar vermal repetitive transcranial magnetic stimulation in schizophrenia: A case report
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The efficacy of cerebellar vermal deep high frequency (theta range) repetitive transcranial magnetic stimulation (rTMS) in schizophrenia: A randomized rater blind-sham controlled study
2016, Psychiatry ResearchCitation Excerpt :These cortical interneurons possibly cause further excitation in areas of the frontal lobe implicated for negative symptoms (medial frontal areas) (Koutsouleris et al., 2008) and mood (anterior cingulated) (Fujimoto et al., 2007). Earlier we, in a case report, showed that cerebellar vermal high frequency rTMS increases frontal resting state EEG gamma power, suggesting that modulation of neuronal networks lead to activation in frontal regions resulting in the improvement in anergia and depression clusters in schizophrenia (Garg et al., 2013). This hypothesis has been supported by PET studies; implicating a putative compensatory mechanism for dysfunctional cerebro-cerebellar circuitry in patients with hypo-frontal/negative symptoms (Kim et al., 2000).
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