Elevated eosinophils, IL5 and IL8 in induced sputum in asthma patients with accelerated FEV1 decline☆
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Keywords
Asthma
Lung function decline
Eosinophils
IL5
IL8
Abbreviations
FEV1
forced expiratory volume in first second
FVC
forced vital capacity
TI
Tiffeneau index
FeNO
exhaled nitric oxide
PD20
provocative dose causing 20% drop
post BD
post bronchodilation
IL
interleukin
IL5-R
interleukin 5 receptor
VEGF
vascular endothelial growth factor
IFNγ
interferon gamma
TGFβ
transforming growth factor beta
BAL
broncho-alveolar lavage
ASM
airway smooth muscle
TNNC
total number of non-squamous cells
ICS
inhaled corticosteroids
LABA
long acting beta agonists
SABA
short acting beta agonist
ACT
asthma control test
BMI
body mass index
SEM
standard error of the mean
IQR
interquartile range
p
probability
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Elevated IL5 and IL8 and eosinophils in induced sputum in asthma patients with accelerated FEV1 decline.
© 2020 Elsevier Ltd.