Images in Clinical RheumatologyPeriprosthetic osteolysis by microparticles mimicking a tumour process in the right hip in 18F-FDG PET/CT studyOsteólisis periprotésica por micropartículas que simula un proceso tumoral en cadera derecha en estudio 18F-FDG PET/TC☆
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Commentary
The particles produced by the friction mechanism of the prosthesis migrate to the prosthesis-bone interface and produce a biological response that causes linear or rounded areas of osteolysis, similar to tumour or infectious processes, leading to loosening and displacement of the prosthesis.1 Macrophages are the cells responsible for the recognition of these particles and the production of pro-inflammatory cytokines that lead to the activation of osteoclasts, which are responsible for
Authors
Manuscript concept and design: Elena Espinosa Muñoz.
Data collection: Elena Espinosa Muñoz.
Data analysis and interpretation: Elena Espinosa Muñoz, Antonio Luis Gutiérrez Cardo, Carmen Puentes Zarzuela.
Writing, review and approval of the manuscript: Elena Espinosa Muñoz, Antonio Luis Gutiérrez Cardo, Carmen Puentes Zarzuela.
Conflict of interests
The authors have no conflict of interests to declare.
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Please cite this article as: Espinosa Muñoz E, Gutiérrez Cardo AL, Puentes Zarzuela C. Osteólisis periprotésica por micropartículas que simula un proceso tumoral en cadera derecha en estudio 18F-FDG PET/TC. Reumatol Clin. 2021;17:425–426.