Elsevier

Research in Microbiology

Volume 169, Issue 10, December 2018, Pages 649-658
Research in Microbiology

Peptides as biosorbents – Promising tools for resource recovery

https://doi.org/10.1016/j.resmic.2018.06.001Get rights and content
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Abstract

Despite many innovations, meeting both economic and ecological requirements remains challenging for conventional resource recovery technology. The development of highly selective peptides puts a new competitor on the market. We present an approach to identify peptides for resource recovery using Phage Surface Display. Here, we describe the development of peptides for binding of rare earth element terbium-containing solids and for removal and enrichment of the heavy metal ions of cobalt and nickel out of waste waters and leaching solutions. We identified phage displaying specific peptides with ∼100× enhanced affinity towards terbium-containing solids or ∼20× enhanced affinity towards nickel (∼3× cobalt).

Keywords

Phage display
Biosorption
Peptide
Biohydrometallurgy
Metallopeptide
Metal binding

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