Research Paper2-Alkenal modification of hemoglobin: Identification of a novel hemoglobin-specific alkanoic acid-histidine adduct
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Graphical abstract
Keywords
Lipid peroxidation
Aldehyde
Hemoglobin
Protein chemical modification
Red blood cells
Abbreviations
LC-ESI-MS/MS
liquid chromatography with electrospray ionization tandem mass spectrometry
PUFA
polyunsaturated fatty acids
HSA
human serum albumin
PP IX
protoporphyrin IX
RBCs
red blood cells
SRM
Selected reaction monitoring
m/z
mass-to-charge ratio
CHH
Nτ-(1-carboxyheptan-2-yl)-histidine
LDL
low-density lipoproteins
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© 2019 The Authors. Published by Elsevier B.V.