A pilot study to compare patient perception of obstructive sleep apnea treatment with CPAP or appliance therapy
Section snippets
Material and Methods
The study was conducted in KG Medical University, Lucknow, India, in the Department of Prosthodontics in collaboration with the Pulmonary Medicine Department after receiving approval from the ethics committee. Patients older than 21 years and younger than 65 years diagnosed with mild to moderate OSA were recruited.
The screening of OSA patients was based on 1-night polysomnography,16 the ESS, and the BQ. The BQ, developed in 1996, comprises 10 questions and is well established in screening
Demographic data
The mean ±SD age of the study participants was 52.06 ±7.2 years (Table I). The age of the MAD group was 49.5 ±8.2 years (median 50 years). The age of the CPAP group was 51.5 ±7.3 years (median 51 years). Twenty-six participants were men (81.3%) and 6 were women (18.7 %). The mean BMI of the participants was 31.3 kg/m2. Approximately 6% of participants were normal weight, 38% were overweight, and 56% were obese. More than 75% of the participants were hypertensive, and a little less than half
Discussion
The null hypothesis of this study could not be rejected. Considering the nonparametric study distribution, the Mann-Whitney U test with 16 participants per group (mean scale score difference of 0.25 for snoring loudness between MAD and CPAP group; Table II) at α=.05 and 95% confidence interval provided a power of 74% (2-sided test). Greater improvement in BQ variables for the CPAP group (compared to the MAD group) was statistically insignificant.
The study used questionnaire-based scales in the
Conclusions
This pilot study found statistically significant posttreatment improvement in participant-perceived OSA symptoms evaluated with the BQ and ESS in both MAD and CPAP groups. An intergroup comparison of this improvement revealed a statistically insignificant difference.
Acknowledgment
The authors thank Prof. Anupam Mishra, Department of Otorhinolaryngology, KG Medical University, Lucknow, India; and Prof. Amit Nagar, Department of Orthodontics, KG Medical University, Lucknow, India.
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