Evaluation of unstimulated flow rates of whole and palatal saliva in healthy patients wearing complete dentures and in patients with Sjogren's syndrome☆
Section snippets
Material and methods
This study included 24 healthy patients referred to the Department of Prosthodontics (Semmelweis University, Dental Faculty, Budapest, Hungary) who served as the study control group, and 11 complete denture-wearing patients with diagnosed Sjogren's syndrome (SS) encountered at the Division of Immunology, (3rd Department of Internal Medicine, Medical and Healthscience Center, University of Debrecen, Hungary). The control subjects were healthy patients with an average age (mean ± SD) of 67 ± 8
Results
None of the control patients but all of the SS patients (11) sensed subjective xerostomia. The ratio of patients with xerostomia was significantly higher in those with SS by the chi-square test (P<.01). Although 3 of the 24 controls and 8 of the 11 SS patients demonstrated hyposalivation (UWS equal to or less than 0.1mL/min), none of the subjects complained of unstable dentures (Table II). The ratio of patients with hyposalivation was significantly higher in the SS group, tested by the
Discussion
Although the UWS flow rate was diminished, it was surprising that the flow rate of PS did not change in patients with SS or in patients with feelings of subjective xerostomia. The null hypothesis that the flow rate of PS is not decreased in SS was accepted. The results of the present study support the results of Lee et al,11 namely, that mucosal wetness and the subjective feeling of xerostomia might be associated more with UWS flow rate than with PS flow rate.
Monsenego et al4 stated that the
Conclusion
The PS flow rate is not significantly decreased in complete denture wearing patients with SS compared to healthy denture wearers. Patients with hyposalivation or xerostomia in the present study did not complain about unstable maxillary dentures because the rate of secretion of palatal mucous saliva was preserved. The placement of new complete dentures did not cause a change in UWS or PS flow rates in healthy patients after 1 week of wear.
Acknowledgements
The authors thank Professor Colin Dawes, Universtiy of Manitoba, for his advice in the preparation of this manuscript.
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This work was supported by OTKA, Hungary Grant No. T-037776 and Grant No. T-034389.