Original articleScreening for Narrow Angles in the Singapore Population: Evaluation of New Noncontact Screening Methods
Section snippets
Study Population and Recruitment
The study had the approval of the ethics review board of the Singapore Eye Research Institute and was performed in accordance with the tenets of the Declaration of Helsinki. In this prospective cross-sectional study, subjects aged >50 years who did not have any ophthalmic symptoms were recruited from a government-run community polyclinic providing primary health care services. This polyclinic serves >10,000 people per month, mainly of lower to middle socioeconomic status with a high proportion
Results
A total of 2114 subjects were screened from December of 2005 to June of 2006. Twelve subjects were ineligible because they were pseudophakic in both eyes or were known to have glaucoma and were excluded. Approximately 90% of subjects were Chinese, with a mean age of 63.3±8.0 years, and 1085 (52.9%) were women (Table 1). Of the 2102 eligible subjects, 50 subjects could not complete the tests for various reasons: alignment errors (12); inability to follow instructions (16) or focus on the
Discussion
The ideal community-based screening test should be clinician-independent, quick, and noninvasive, and have a very high specificity. Although a high sensitivity is important, the choice of the specific thresholds used to trigger a referral for examination is as much a question of public health and health economics issue as a clinical one. The severity of the disease and its impact on the national economy and personal finances need to be balanced against individual and national costs of testing,
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Manuscript no. 2007–1464.
Financial Disclosure(s): Dr Kashiwagi has a Japanese patent on the SPAC (Japanese patent No. 3878164). Dr Friedman has been a paid consultant to Carl Zeiss-Meditec. Dr Foster has received honoraria and travel support from Carl Zeiss Meditec. Dr Aung has received research funding and travel support from Carl Zeiss Meditec.
Supported by a grant from Singhealth Foundation, Singapore. The authors' work was independent of the funders (the funding source had no involvement).
These authors (R.L. and P.J.F.) contributed equally to this work.