Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Oral medicineQuality of life in patients with oral potentially malignant disorders: a systematic review
Section snippets
Literature search
The present systematic review is registered with International Prospective Register of Systematic Reviews (Registration number: CRD42013006239). The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were followed.34 The databases searched for relevant articles included PUBMED, MEDLINE via OVID, and CINAHL Plus via EBSCO. Definite keywords that constitute OPMDs6 were used. Further, the keywords “oral precancerous lesion,” “oral precancerous condition,” “stomatological
Results
Figure 1 presents the information on publications screened, assessed for eligibility, and included in the review. The search from PUBMED retrieved 148 articles, whereas that in MEDLINE and CINAHL Plus via EBSCO databases yielded 79 and 30 titles, respectively. Thus, a total of 257 titles were obtained from the electronic search and 180 titles were left for screening after removing duplicates; additionally, 4 articles were retrieved by hand searching. The titles and abstracts of 184 articles
Discussion
Quality of life is gaining importance in public health research and practice and is being recognized more as a valid and important indicator of service need and intervention outcomes.50 The present systematic review evidences the paucity of literature on QoL in OPMDs compared with the abundant literature on QoL in patients with oral cancer. A general search in PUBMED using the terms “oral cancer” AND “quality of life” would yield more than 200 relevant articles.
The quality of the majority of
Conclusions
There is no strong evidence that patients with OPMDs have a poorer QoL compared with healthy patients. Several things may explain this superficially surprising conclusion. First, the quality of most of the articles included in this review was moderate or weak; second, most of the studies assessed QoL only in patients with OLP, and these cannot be generalized to all patients with OPMDs; finally, direct comparisons between patients with OPMDs and healthy controls were rarely included. The
References (62)
- et al.
A structured review and theme analysis of papers published on ‘quality of life’ in head and neck cancer: 2000-2005
Oral Oncol
(2007) - et al.
A prospective study on quality of life of patients with cancer of the oral cavity or oropharynx treated with surgery with or without radiotherapy
Oral Oncol
(1999) Actinic keratosis: from the skin to the lip
J Oral Maxillofac Surg
(2008)Oral manifestations in the epidermolysis bullosa spectrum
Dermatol Clin
(2010)Potentially malignant disorders of the oral and oropharyngeal mucosa: terminology, classification and present concepts of management
Oral Oncol
(2009)- et al.
Oral erythroplakia—a review
Oral Oncol
(2005) - et al.
A systematic review of head and neck cancer quality of life assessment instruments
Oral Oncol
(2012) - et al.
Health-related quality of life in oral cancer: a review
J Oral Maxillofac Surg
(2006) - et al.
Quality-of-life measurement in blistering diseases
Dermatol Clin
(2012) - et al.
Patient-centred outcome measures in oral medicine: are they valid and reliable?
Int J Oral Maxillofac Surg
(2002)