Elsevier

Revue Neurologique

Volume 177, Issue 6, June 2021, Pages 707-708
Revue Neurologique

Letter to the Editor
Paroxysmal dyskinesia: When a PRRT2 variant hides a curable cause

https://doi.org/10.1016/j.neurol.2020.09.012Get rights and content

Section snippets

Case report

A 70 year-old man with a personal history of hypertension developed, at age 67, recurrent choreo-dystonic episodes, affecting initially the right inferior limb, then, after a few months, the four limbs (Video). They occurred preferentially after prolonged walking, but also at rest, lasting from thirty to sixty minutes, firstly every three or four months, then every week, preferably outside mealtimes. Attacks were associated with diaphoresis, intense feeling of hunger, confusion, personality

Discussion

Main PD metabolic causes are hypoglycemia and hypocalcemia, so that fasting glucose and calcium dosages should always be tested in front of PD [1]. Glucose level analysis should, in some cases, be repeated, and in our case, despite a fasting glucose level inside the laboratory limits, associated neuroglycopenic symptoms (confusion, personality changes…), and autonomic symptoms (diaphoresis, feeling of hunger…) should have led earlier to the diagnosis of insulinoma [2]. Among glycopenic

Data availability statement

Data openly available in a public repository that issues datasets with DOIs.

Disclosure of interest

The authors declare that they have no competing interest.

References (5)

There are more references available in the full text version of this article.

Cited by (0)

View full text