bFGF-incorporated composite biomaterial for bone regeneration
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open access
Graphical abstract
RADA16 peptide solution and bFGF were combined to form bFGF-incorporated hydrogel, which were immediately to fill the porosity and surface of CaSO4/HA cement material. The injectable RADA16+bFGF/CaSO4/HA composite biomaterial can promote osteogenic differentiation in vitro and bone formation in vivo for bone defect.
Keywords
Bone defect
RADA16/CaSO4/HA
Controlled release
Osteogenic differentiation
Bone formation
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© 2022 The Author(s). Published by Elsevier Ltd.