Original ArticleClinical and Radiographic Natural History of Cervical Artery Dissections
Section snippets
Methods
Our stroke center databases, which include patients seen in the inpatient (ward and intensive care department) and outpatient settings, were searched from January 1992 to December 2006 for patients identified as having a CAD. The study was approved by our institutional review board. Only patients who had definitive clinical and supportive radiographic evidence of an extracranial ICA or VA dissection were included for analysis. Namely, patients needed to have one or more characteristic
Results
Of the approximately 8800 patients in our databases, we identified 177 (103 men, 74 women; mean age 44.1 ± 11.1 years) who met entry criteria (Table 1). Overall, dissection occurred more commonly in men than in women (P = .03). The mean age of the women (41.6 ± 10.9 years; range 17-64) was lower than that of the men (45.8 ± 10.9; range 16-76; P = .01). Hyperlipidemia and hypertension were the most commonly seen traditional vascular risk factors, and were significantly more prevalent in men.
Discussion
The mean age of our dissection population (44.1 years) is consistent with previously reported series.7, 19, 20, 21, 22, 23, 24 Overall, dissection occurred more commonly in men than in women, but men were more likely to have trauma as a mechanism; spontaneous dissections had approximately equal occurrences between the sexes. Overall, the mean age of the women was significantly lower than that of the men, a result that has been previously noted but not well understood.4, 21 A large number of our
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