PathologyOral Papillomatosis in Immunocompromised Patients: A Case Series of Kidney Transplant Recipients and Myelodysplastic Syndrome
Section snippets
Case 1
A 51-year-old man visited the department of advanced general dentistry for discomfort caused by tooth extrusion. He had a medical history of 2 kidney transplantations 26 and 15 years previously, respectively. He had been taking tacrolimus and mycophenolate mofetil since then.
During oral examination, 3 pedunculated, clustered, whitish-pink papillary lesions (central, 15 × 6 × 5 mm; left, 12 × 4 × 4 mm; right, 6 × 6 × 5 mm) at the floor of the mouth and another separate pedunculated papillary
Discussion
Oral squamous papilloma is a benign papillary epithelial tumor believed to be associated with low-risk HPV 6 or 11 infection. Usually, it is a solitary lesion and has a maximum growth of 5 mm in diameter.18 Multiple growths of squamous papillomas are relevant to recurrent respiratory papillomatosis (RRP), which is frequently associated with HPV type 6 and 11 infections. RRP can involve any part of the aerodigestive tract but has a predilection for the larynx and has been discussed in relation
References (27)
- et al.
New trends in immunosuppression and immunotherapy
Int Immunopharmacol
(2006) - et al.
The impact of infection on chronic allograft dysfunction and allograft survival after solid organ transplantation
Am J Transpl
(2015) - et al.
Immunosuppressive drugs and cancer
Toxicology
(2003) - et al.
New concepts and best practices for management of pre- and post-transplantation cancer
Transpl Rev (Orlando)
(2012) - et al.
Oral manifestations in myelodysplastic syndrome. Review of the literature and report of a case
Oral Surg Oral Med Oral Pathol
(1986) - et al.
The myelodysplastic syndromes. Case report and review
Oral Surg Oral Med Oral Pathol
(1990) - et al.
Lip cancer in renal transplant patients
Oral Oncol
(2011) - et al.
The need for minimization strategies: Current problems of immunosuppression
Transpl Int
(2015) - et al.
Anogenital malignancies in women after renal transplantation over 40 years in a single center
Transplantation
(2012) - et al.
Oral lesions in organ transplant patients
J Oral Pathol Med
(1997)
Oral lesions in renal transplant
J Craniofac Surg
Comparison of oral lesion prevalence in renal transplant patients under immunosuppressive therapy and healthy controls
Oral Dis
Presence of Epstein-Barr virus, cytomegalovirus and human papillomavirus in normal oral mucosa of HIV-infected and renal transplant patients
Oral Dis
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Dr Kwak and Dr Choi contributed equally to this article.
This research was supported by the Basic Science Research Program through the National Research Foundation of Korea funded by the Ministry of Science, ICT and Future Planning (NRF-2017R1C1B1012464).
Conflict of Interest Disclosures: None of the authors have a relevant financial relationship(s) with a commercial interest.