Oral presentationPlenary 16—Endometriosis128: Determinants of Clinically Detected Long-Term Recurrence Rates of Deep, Ovarian, and Pelvic Endometriosis
Section snippets
Study Objective
To analyze the frequency and the determinants of long term recurrence rate of clinically detectable deep, ovarian and pelvic endometriosis.
Design
Retrospective analysis of clinical data of 1239 consecutive women who underwent laparoscopic or laparotomic surgery for endometriosis between 1979 and 2001.
Setting
University hospital, gynecological department, Luigi Mangiagalli Hospital, Milan, Italy.
Patients
Eligible for the study were women with a laparoscopically or laparotomically confirmed first diagnosis of endometriosis. A total of 1239 women (median age 32 years) entered the study. The mean number of calendar year was 51 (range 20-68). A total of 123 women were lost to follow up immediately after surgery, thus the present paper include information on 1106 patients.
Intervention
Laparoscopic and laparotomic procedures.
Measurements and Main Results
All women were followed each year with a clinical examination, an U.S. pelvic examination and CA 125 assay. Four and 8 years recurrence probabilities were estimated: Women lost at follow up were considered in the analysis for the period during which they were in the trial. The 4 years recurrence rate was 24.6%, 17.8%, 30.6% and 23.7% respectively in case of ovarian, pelvic, deep, ovarian and pelvic endometriosis. The recurrence rate increase constantly with the time from diagnostic surgery in
Conclusion
The study offers information on determinants of recurrence of endometriosis at different sites on a large sample. The risk factors are similar at different sites and in young and older women.