Elsevier

Journal of Cardiology

Volume 81, Issue 1, January 2023, Pages 10-18
Journal of Cardiology

Review
Recent advances on nanoparticle-based therapies for cardiovascular diseases

https://doi.org/10.1016/j.jjcc.2022.02.009Get rights and content
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Highlights

  • Nanoparticles based therapeutics for cardiovascular disease.

  • Application of nanoparticles in biomedical imaging for cardiovascular disease diagnosis.

  • Multifunctional nanoparticles in targeted drug delivery.

Abstract

Nanoparticles are exclusively suitable for studying and developing potential therapies against cardiovascular diseases (CVD) because of their size, fine-tunable properties, and ability to incorporate therapeutic and imaging modalities. Recent advancements in nanomaterials open new avenues for treating CVD. In cardiology, the use of nanoparticles and nanocarriers has gathered significant consideration owing to characteristic features such as active and passive targeting to the cardiac tissues, greater target specificity, and sensitivity. It has been reported that through the use of nanotechnology, more than 50% of CVDs can be treated efficiently. Heart-targeted nano carrier-based drug delivery is an effective and efficient approach for treating cardiac-related disorders such as atherosclerosis, hypertension, and myocardial infarction. In this review, the authors focus on nanoparticle-based therapies used in CVD and provide an outline of essential knowledge and critical concerns on polymer-based nanomaterials in treating CVD.

Keywords

Cardiovascular diseases
Nanotechnology
Nanocarriers

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