Incidence and economic burden of acute otitis media in children aged up to 5 years in three Middle Eastern countries and Pakistan: A multinational, retrospective, observational study

Ghulam Mustafa; Amal Y. Al Aidaroos; Idris S. Al Abaidani; Kinga Meszaros; Kusuma Gopala; Mehmet Ceyhan; Mohamad Al-Tannir; Rodrigo DeAntonio; Shyam Bawikar; Johannes E. Schmidt

doi:10.1016/j.jegh.2016.12.004

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Volume 7, Issue 2, June 2017, Pages 123 - 130

Incidence and economic burden of acute otitis media in children aged up to 5 years in three Middle Eastern countries and Pakistan: A multinational, retrospective, observational study

Authors

Ghulam Mustafa^a^{, 1}, Amal Y. Al Aidaroos^b^{, 1}, Idris S. Al Abaidani^c^{, 1}, Kinga Meszaros^d, Kusuma Gopala^e, Mehmet Ceyhan^f, Mohamad Al-Tannir^g^{, 1}, Rodrigo DeAntonio^h, Shyam Bawikarⁱ, Johannes E. Schmidt^j^{, *}^,johannes.e.schmidt@gsk.com

^aDepartment of Pediatrics, Institute of Mother & Child Care, Multan, Pakistan

^bPrince Sultan Military Medical City, Pediatric Infectious Diseases, Riyadh, Saudi Arabia

^cCommunicable Disease Surveillance & Control, Muscat, Oman

^dGSK, Wavre, Belgium

^eGSK, Bangalore, India

^fHacettepe University Medical Faculty, Paediatric Infectious Diseases, Ankara, Turkey

^gKing Fahad Medical City, Research Centre, Riyadh, Saudi Arabia

^hGSK, Ciudad del Saber, Panama

ⁱMinistry of Health, Communicable Disease Surveillance & Control, Directorate General of Health Affairs, Ministry of Health HQ, Muscat, Oman

^jGSK, Siena, Italy

¹

All principal investigators have contributed equally to the study.

^* Corresponding author at: Clinical RDC Italy, GSK, Via Fiorentina, 1, 53100 Siena SI, Italy.

Corresponding Author

Johannes E. Schmidtjohannes.e.schmidt@gsk.com

Received 7 April 2016, Revised 1 December 2016, Accepted 10 December 2016, Available Online 8 February 2017.

DOI: 10.1016/j.jegh.2016.12.004 How to use a DOI?
Keywords: Acute otitis media; Economic burden; Incidence; Middle east
Abstract: Epidemiological data on acute otitis media (AOM), an infectious disease frequently affecting children, are lacking in some countries. This study was undertaken to assess the incidence of AOM in children ≤5 years in Saudi Arabia, Oman, Pakistan, and Turkey, as well as the economic burden from a parent/caregiver perspective. Medical records of 4043 children (Saudi Arabia = 1023, Oman = 998, Pakistan = 1022, Turkey = 1000) were retrospectively reviewed and the incidence of AOM episodes calculated from suspected and confirmed cases. Using a standardized Health Economics Questionnaire, parents recorded resource use and expenses incurred per AOM episode [in local currency and converted to US dollars (USD)]. The overall incidence of AOM episodes per 1000 person–years was: Saudi Arabia, 207 [95% confidence interval (CI): 178–238]; Oman, 105 (95% CI: 85–127); Pakistan, 138 (95% CI: 116–163); and Turkey, 99 (95% CI: 79–123). The mean total out-of-pocket healthcare expense incurred by parents/caregivers per episode was: Saudi Arabia USD67.1 [standard deviation (SD) = 93.0], Oman USD16.1 (SD = 16.4), Pakistan USD22.1 (SD = 20.5), and Turkey USD33.6 (SD = 44.9). The incidence of AOM episodes varied across all four countries, probably due to different diagnostic and management practices. Nevertheless, our results confirm that AOM causes a substantial burden to public health, reinforcing the need for cost-effective prevention strategies.
Open Access: This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Journal: Journal of Epidemiology and Global Health
Volume-Issue: 7 - 2
Pages: 123 - 130
Publication Date: 2017/02/08
ISSN (Online): 2210-6014
ISSN (Print): 2210-6006
DOI: 10.1016/j.jegh.2016.12.004 How to use a DOI?
Open Access: This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

Cite this article

ris enw bib

TY  - JOUR
AU  - Ghulam Mustafa
AU  - Amal Y. Al Aidaroos
AU  - Idris S. Al Abaidani
AU  - Kinga Meszaros
AU  - Kusuma Gopala
AU  - Mehmet Ceyhan
AU  - Mohamad Al-Tannir
AU  - Rodrigo DeAntonio
AU  - Shyam Bawikar
AU  - Johannes E. Schmidt
PY  - 2017
DA  - 2017/02/08
TI  - Incidence and economic burden of acute otitis media in children aged up to 5 years in three Middle Eastern countries and Pakistan: A multinational, retrospective, observational study
JO  - Journal of Epidemiology and Global Health
SP  - 123
EP  - 130
VL  - 7
IS  - 2
SN  - 2210-6014
UR  - https://doi.org/10.1016/j.jegh.2016.12.004
DO  - 10.1016/j.jegh.2016.12.004
ID  - Mustafa2017
ER  -

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