Selection of chromatographic methods for the purification of cell culture-derived Orf virus for its application as a vaccine or viral vector
Abbreviations
DBC
dynamic binding capacity
DLS
dynamic light scattering
HIC
hydrophobic interaction chromatography
HICP
HIC membrane adsorber with phenyl ligand
IEX
ion exchange chromatography
IEX-Q
strong anion exchanger (Quaternary ammonium)
IEX-S
strong cation exchanger (Methyl sulfonate)
IEX-STPA
salt tolerant polyamide anion exchanger
IU
infective units
MVA
Modified Vaccinia Ankara virus
PEG
polyethylene glycol
pI
isoelectric point
SCMA
sulfated cellulose membrane adsorber
SEC
size exclusion chromatography
SXC
steric exclusion chromatography
TCID50
fifty-percent tissue culture infective dose
Keywords
Parapoxvirus
Viral vector
Steric exclusion chromatography
Isoelectric point
Cited by (0)
© 2020 Elsevier B.V. All rights reserved.