Clinical research: percardial disease
Transient constrictive pericarditis: causes and natural history

https://doi.org/10.1016/j.jacc.2003.08.032Get rights and content
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Abstract

Objectives

This study was designed to elucidate the causes and natural history of transient constrictive pericarditis (CP).

Background

In some patients with acute CP, the symptoms and constrictive physiologic features resolve with medical therapy alone, a phenomenon that has been labeled “transient constrictive pericarditis.” No large studies have examined the causes or natural history of transient CP.

Methods

Review of the Mayo Clinic echocardiogram database identified 212 patients who had echocardiographic findings of CP from 1988 through 1999. Demographic, clinical, and echocardiographic findings were identified in all patients. In 36 of these patients, follow-up echocardiograms showed resolution of the constrictive hemodynamics without pericardiectomy.

Results

The average age of the patients was 49 ± 21 years, and 72% were men. The causes for the CP were diverse, the most common being prior cardiovascular surgery (25%). In a subset of 22 patients who were followed serially during the course of their illness, resolution of the constrictive physiologic features occurred at an average of 8.3 weeks after diagnosis.

Conclusions

A subset of patients with CP experience resolution of the disorder without requiring pericardiectomy.

Abbreviations

CP
constrictive pericarditis
NSAID
nonsteroidal anti-inflammatory drug
PE
pericardial effusion

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