Journal of American Association for Pediatric Ophthalmology and Strabismus
Major ArticleValidation of the Pediatric Vision Scanner in a normal preschool population
Section snippets
Subjects and Methods
Kaiser Permanente Southern California (KPSC) Institutional Review Board approval was obtained for this study, which adhered to the tenets of the Declaration of Helsinki and was registered on ClinicalTrials.gov (NCT02536963).
Results
Of the 318 children enrolled in the study, 18 were excluded from analysis; we were unable to obtain reliable PVS results from 3 children due to device malfunction and from 8 children due to lack of cooperation. An additional 7 patients left the clinic before completing the eye examination. Of the 300 children included in the analysis, 141 were female (47%) and 149 were male (53%). The median age was 48 months. With regard to race, 121 participants (40.3%) were non-Hispanic white, 80 (26.7%)
Discussion
Screening preverbal children with instrument-based screening can be fraught with poor specificity, false positives, and unnecessary referrals.13 In a prior study examining the PVS in a similar primary care cohort, Jost and colleagues11 reported data for 100 children; however, they screened nearly 300 children, with only one-third presenting for follow-up examination. In their study, 1 patient who had amblyopia on examination was also detected on PVS screening. The small numbers in that study
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Financial support: Rebiscan Inc. (dba Rebion), Boston, MA, and National Institutes of Health (National Eye Institute), Bethesda, MD (R44EY025926). The funding organizations had no role in the design or conduct of this research.