Editorial
What Are the Transgenerational Consequences of Maternal Childhood Adversity and Maternal Stress During Pregnancy?

https://doi.org/10.1016/j.jaac.2017.09.421Get rights and content

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Cited by (2)

  • Correlation of Gut Microbiome Between ASD Children and Mothers and Potential Biomarkers for Risk Assessment

    2019, Genomics, Proteomics and Bioinformatics
    Citation Excerpt :

    Although the causes of ASD are not yet known, it is generally believed that genetic, epigenetic, and environmental risk factors interact and all play roles in the development of ASD [11,12]. Epidemiological and animal-based studies have suggested that inflammation-induced maternal immune activation, prenatal exposure to immune challenges, and maternal obesity, stress, and gastrointestinal symptoms during pregnancy play roles in perinatal neurodevelopmental brain damage and contribute to an increased risk of subsequent neuropsychiatric disorders, such as ASDs [13–17]. In recent years, there has been a lot of epidemiological and biological evidence that prenatal factors trigger a more active immune state in the mother, which is associated with the development of autism [9,13–16,18–20].

  • A Multi-Cohort Examination of the Independent Contributions of Maternal Childhood Adversity and Pregnancy Stressors to the Prediction of Children’s Anxiety and Depression

    2023, Research on Child and Adolescent Psychopathology

This editorial was reviewed under and accepted by Assistant Editor Robert R. Althoff, MD, PhD.

Disclosure: Dr. Leckman has received grant or research support from the National Institutes of Health. He has served on the advisory boards of the Brain and Behavior Research Foundation, the National Organization for Rare Disorders, Fondazione Child, the European Muilticentre Tics in Children Studies, and How I Decide. He has authored the Yale Global Tic Severity Scale (YGTSS) assessment tool, which is open access. He has served as a consultant to Tasly Pharmaceuticals, Inc. He has received honoraria from the Brazilian Psychiatric Association. He has received royalties from John Wiley and Sons, McGraw Hill, and Oxford University Press. He has received travel expenses from the Brazilian Psychiatric Association, Queen's University Belfast, and Tasly Pharmaceuticals, Inc. He has received additional support from private donors.

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©2017 American Academy of Child and Adolescent Psychiatry