Small bowel malignancy

doi:10.1016/j.giec.2003.10.006

Gastrointestinal Endoscopy Clinics of North America

Volume 14, Issue 1, January 2004, Pages 139-148

https://doi.org/10.1016/j.giec.2003.10.006 Get rights and content

Section snippets

Standard diagnostic techniques for small bowel malignancies

Endoscopy (upper GI endoscopy, colonoscopy, push-enteroscopy [PE]), barium studies, computed tomography (CT), and in selected cases angiography are the standard techniques that can be used for the diagnosis of small bowel malignancies.

Capsule endoscopy in the diagnosis of small bowel malignancies

Capsule endoscopy (CE) has the potential to explore the entire small bowel; therefore, it has a theoretical advantage over PE, which can only explore the jejunum, as well as over SBFT and enteroclysis, which are unsuitable to detect small mucosal lesions, especially in the distal ileum. So far, only one study, published in abstract form, was aimed specifically at evaluating the diagnostic yield of CE [6] for small bowel tumors. This is a retrospective study of 100 patients studied with CE; in

Summary

CE is an exciting new tool for the diagnosis of small bowel diseases. As far as the diagnosis of tumors is concerned, we have only begun to explore the potential of this technique. New studies are badly needed to establish the usefulness of CE in the diagnosis and management of small bowel malignancies. Such studies should help establishing the most appropriate place for CE in this setting.

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Cited by (54)

Small bowel tumors: A digestive endoscopy society of Taiwan (DEST) multicenter enteroscopy-based epidemiologic study
2018, Journal of the Formosan Medical Association
Citation Excerpt :
Small bowel (SB) presents the majority of the gastrointestinal (GI) tract length and absorptive surface; however, malignancies of SB account for only 1–3% of all GI tract malignancies.1–5
Small bowel (SB) accounts for the majority of gastrointestinal tract but its tumors are rare and always overlooked. In this study, we aimed to evaluate the epidemiology of SB tumors.
This multicenter retrospective study utilized endoscopy database from 2006/11 to 2016/07. Baseline demographic characteristics, clinical, radiologic and endoscopic findings were collected.
Totally 103 (34 benign, 69 malignant lesions) patients with SB tumors in 1070 enteroscopic examinations were enrolled. There were male preponderance (56.3% males, 43.7% females), both in benign (52.9%, 49.1%) and malignant (58.0%, 42.0%) lesions, except for subtype gastrointestinal stromal tumors (GISTs) (31.6%, 68.4%). The age (mean ± SD) at diagnosis in malignant SB tumors (62.2 ± 15.6) was older than those with benign tumors (50.7 ± 21.4) (p < 0.01). Bleeding (43.7%), abdominal pain (40.8%) and ileus (10.7%) were the most common clinical presentations. Hamartoma (32.4%) and adenoma (14.7%) were the most common benign histology. Four major malignant histological subtypes were lymphomas (29.0%), GISTs (27.5%), adenocarcinomas (26.1%) and metastatic cancers (14.5%). SB adenocarcinoma patients (>60-year-old, 77.8%) were older than lymphomas (60%) and GISTs (50%). Proximally location rates of lymphomas, GISTs, adenocarcinomas were 25.0% (5/20), 84.2% (16/19), and 88.9% (16/18), respectively.
This endoscopy-based study revealed the most common histology of benign SB tumors were hamartoma and adenoma, and malignant ones were lymphomas, GISTs, adenocarcinomas and metastatic cancers. Most of them were male gender, except for GISTs, and with proximal location, except for lymphomas. Further large-scale investigation efforts are warranted to elucidate the epidemiology of SB tumors.
Evaluation and management of small-bowel tumors in the era of deep enteroscopy
2014, Gastrointestinal Endoscopy
Citation Excerpt :
CE is a safe and noninvasive test for study of the entire small bowel, which is both well-accepted by patients and effective in diagnosing small-bowel disease. The small-bowel tumor detection rate for CE has ranged from 2% to 9% in patients mainly presenting with GI bleeding.4,34-37 When the National Cancer Institute's Surveillance, Epidemiology, and End Results Program 9 Incidence database was used, the average annual age-adjusted incidence of small-bowel cancer nearly doubled from 11.8 cases per million in 1973 to 22.7 cases per million in 2004, after the introduction of CE.38
Clinicopathological features of small bowel tumors diagnosed by video capsule endoscopy and balloon-assisted enteroscopy: A single center experience
2021, Clinical Endoscopy
Automatic detection of small bowel tumors in wireless capsule endoscopy images using ensemble learning
2020, Medical Physics
Diagnostic value and safety of emergency single-balloon enteroscopy for obscure gastrointestinal bleeding
2019, Gastroenterology Research and Practice
Structural dynamics and evolution of capsule endoscopy (Pill Camera) technology in gastroenterologists assertion
2018, arXiv

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View full text

Small bowel malignancy

Section snippets

Standard diagnostic techniques for small bowel malignancies

Capsule endoscopy in the diagnosis of small bowel malignancies

Summary

First page preview

Gastroenterology

Am J Gastroenterol

Dig Liver Dis

Incidence of histologic types of cancer of the small intestine

J Natl Cancer Inst

Primary malignancies of the small bowel: a report of 96 cases and review of the literature

Ann Surg

Long-term outcome of patients with gastrointestinal bleeding of obscure origin explored by push enteroscopy

Endoscopy

Radiography in primary tumors of the small bowel

Acta Radiol

Small bowel enema. An underutilized method of small bowel examination

Dig Dis Sci

Retrospective analyses of cases of small bowel tumours detected by capsule endoscopy

Endoscopy

A comparison between the M2A capsule and push enteroscopy for the investigation of obscure gastrointestinal bleeding

J Gastroenterol Hepatol

The first prospective controlled trial comparing wireless capsule endoscopy with push enteroscopy in chronic gastrointestinal bleeding

Endoscopy

Capsule endoscopy in clinical practice

Diagnostic yield of capsule endoscopy in patients with severe GI bleeding of obscure origin, subsequent recommendations and outcomes

Video capsule endoscopy: early observations on its role in the diagnosis and management of obscure gastrointestinal bleeding

Gastrointest Endosc

Evaluation of bleeding of undetermined origin by wireless endoscopy

Gastrointest Endosc

Video capsule endoscopy in the evaluation of obscure gastrointestinal bleeding

Capsule endoscopy in obscure gastrointestinal bleeding

Clinical results of wireless capsule endoscopy

Gastrointest Endosc

A prospective comparative study of capsule vs. push enteroscopy in obscure gastrointestinal bleeding

Wireless capsule endoscopy: a new dimension in small bowel diagnostics

Gastrointest Endosc

A comparison between the M₂A capsule and push enteroscopy for the investigation of obscure gastrointestinal bleeding