Original articleClinical endoscopyHigh yield of synchronous lesions in referred patients with large lateral spreading colorectal tumors
Section snippets
Methods
This is a retrospective evaluation of a prospectively created database of LLSTs (≥20 mm in size) referred to and resected by a single endoscopist (D.K.R.) between April 2000 and December 2015. Review of the database was approved by the Institutional Review Board at Indiana University Health Partners on June 16, 2015.
In many cases the LLST was removed during the baseline colonoscopy but the entire colon was not cleared until the first follow-up colonoscopy. Patients were encouraged to return to
Results
There were 1029 consecutive patients with sessile or flat lesions ≥ 20 mm in diameter identified in the database; 296 patients were excluded because they only had 1 colonoscopy performed by our endoscopist (D.K.R.). Patients had only 1 colonoscopy if they did not return to our center for follow-up (n = 239), if they were referred for surgical resection because the index lesion had endoscopic features of cancer (biopsy samples were taken from the lesions and patients referred to surgery, n =
Discussion
In this report we describe the prevalence of synchronous lesions in 728 primarily referred patients with large flat or sessile colorectal lateral spreading tumors who underwent colonoscopic clearance over 2 colonoscopies by a single expert endoscopist. The prevalence of synchronous conventional adenomas and synchronous serrated class lesions was very high. Our study indicates that patients with large sessile or flat lateral spreading tumors ≥ 20 mm in size demand detailed clearance of the colon
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Cited by (0)
DISCLOSURE: The following author received research support for this study from a gift from Scott and Kay Schurz and their family of Bloomington, Indiana to the Indiana University Foundation: D. K. Rex. In addition, the following author disclosed financial relationships relevant to this publication: D. K. Rex: Consultant for Olympus. All other authors disclosed no financial relationships relevant to this publication.
If you would like to chat with an author of this article, you may contact Dr Rex at [email protected].