Elsevier

Fertility and Sterility

Volume 96, Issue 2, August 2011, Pages 452-458
Fertility and Sterility

Original article
Reproductive endocrinology
Polycystic ovary syndrome is associated with negatively variable impacts on domains of health-related quality of life: evidence from a meta-analysis

https://doi.org/10.1016/j.fertnstert.2011.05.072Get rights and content
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Objective

To systematically review the literature to identify the impact of polycystic ovary syndrome (PCOS) on specific health-related quality of life domains.

Design

Meta-analysis.

Setting

N/A.

Patient(s)

The outcomes of 423 patients and 285 controls from 5 articles that used the Short Form 36 (SF-36) questionnaire were used for meta-analysis.

Intervention(s)

N/A.

Main Outcome Measure(s)

The SF-36 dimensions including physical function, physical role function, body pain, general health, vitality, social function, emotional role function, and mental health were evaluated.

Result(s)

Compared with controls, women with PCOS had lower scores in all SF-36 dimensions: physical function (mean differences [MD], −5.46; 95% confidence intervals [CI], −8.52, −2.41), physical role function (MD, −5.76; 95% CI, −8.49, −3.03), body pain (MD, −4.55; 95% CI, −7.99, −1.11), general health (MD, −11.34; 95% CI, −19.53, −3.15), vitality (MD, −15.14; 95% CI, −17.43, −12.84), social function (MD, −15.95, 95% CI, −18.57, −13.33), emotional role function (MD, −23.86; 95% CI, −27.51, −20.21), and mental health (MD, −13.83; 95% CI, −16.13, −11.53).

Conclusion(s)

The meta-analysis showed that women with PCOS score lower in each dimension of the SF-36, mostly in the emotional role function.

Key Words

Polycystic ovary syndrome
SF-36
quality of life
meta-analysis

Cited by (0)

Y.L. has nothing to disclose. Y.L. has nothing to disclose. E.H.Y.N. has nothing to disclose. E.S-V. has nothing to disclose. L.H. has nothing to disclose. T.W. has nothing to disclose. F.H. has nothing to disclose. X.W. has nothing to disclose.

Supported by the National Clinical Trial Base of Chinese Medicine in Gynecology (http://www.satcm.gov.cn/zhuanti/lcyjjd/tzgg/20090519/130039.shtml), National Public Welfare Projects for Chinese Medicine (201107005; 200807021).

Yanan Li and Yan Li contributed equally to this work.