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Correlations between cognitive performances and psychotic or schizotypal dimensions

Published online by Cambridge University Press:  16 April 2020

Andrei Szöke ,
Alexandre Méary ,
Aziz Ferchiou ,
Anca Trandafir ,
Marion Leboyer  and
Franck Schürhoff
Andrei Szöke*
Affiliation:
INSERM U955, 94000Créteil, France Université Paris 12, Faculté de Médecine, IFR 10, 94000, Créteil, France AP-HP, Groupe “Chenevier-Mondor”, Pôle de Psychiatrie, 94000Créteil, France
Alexandre Méary
Affiliation:
INSERM U955, 94000Créteil, France Université Paris 12, Faculté de Médecine, IFR 10, 94000, Créteil, France AP-HP, Groupe “Chenevier-Mondor”, Pôle de Psychiatrie, 94000Créteil, France
Aziz Ferchiou
Affiliation:
INSERM U955, 94000Créteil, France Université Paris 12, Faculté de Médecine, IFR 10, 94000, Créteil, France AP-HP, Groupe “Chenevier-Mondor”, Pôle de Psychiatrie, 94000Créteil, France
Anca Trandafir
Affiliation:
AP-HP, Groupe “Chenevier-Mondor”, Pôle de Psychiatrie, 94000Créteil, France
Marion Leboyer
Affiliation:
INSERM U955, 94000Créteil, France Université Paris 12, Faculté de Médecine, IFR 10, 94000, Créteil, France AP-HP, Groupe “Chenevier-Mondor”, Pôle de Psychiatrie, 94000Créteil, France
Franck Schürhoff
Affiliation:
INSERM U955, 94000Créteil, France Université Paris 12, Faculté de Médecine, IFR 10, 94000, Créteil, France AP-HP, Groupe “Chenevier-Mondor”, Pôle de Psychiatrie, 94000Créteil, France
*
*Corresponding author. Pôle de Psychiatrie, Hôpital “A. Chenevier”, 40, rue de Mesly, 94000 Créteil, France. Tel.: +33 (0) 149813051; fax: +33 (0) 149813059. E-mail address: andrei.szoke@ach.aphp.fr
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Abstract

Objective

To test if specific correlations exist between cognitive measures and psychotic dimensions in schizophrenic subjects and if similar correlations, between cognition and schizotypal dimensions, are present in non-psychotic subjects.

Methods

We administered the same battery of cognitive tests (Source Monitoring, Verbal Fluency [VF] and Stroop tests) to schizophrenic subjects (N = 54), their first-degree relatives (N = 37) and controls (N = 41). Scores of negative, positive and disorganisation dimensions were derived from the Signs and Symptoms of Psychotic Illness scale in schizophrenic subjects, and from the Schizotypal Personality Questionnaire in relatives and controls.

Results

In schizophrenic subjects, as hypothesised, the negative dimension correlated with performance on VF and disorganisation with performance in the Stroop test. The positive dimension did not correlate with any cognitive measure.

With only one exception, the significant correlations observed in non-psychotic subjects did not match correlations seen in schizophrenic subjects. In non-psychotic subjects greater disorganisation was associated with more clustered words in VF suggesting that excessive automatic spreading of activation in semantic networks could underlie this dimension.

Conclusion

As a whole, data lent partial support to our hypothesis of specific cognitive–clinical correlations in schizophrenic subjects but did not support the existence of similar correlations in non-psychotic subjects.

Keywords

SchizophreniaSchizotypalDisorganisationCognitionVerbal fluency
Type
Original article
Information
European Psychiatry , Volume 24 , Issue 4 , May 2009 , pp. 244 - 250
Copyright
Copyright © Elsevier Masson SAS 2009

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