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The association between the Lie scale of the Maudsley personality inventory and striatal dopamine D2/D3 receptor availability of healthy Chinese community subjects

Published online by Cambridge University Press:  16 April 2020

Chieh Liang Huang ,
Yen Kuang Yang ,
Ching Lin Chu ,
I Hui Lee ,
Tzung Lieh Yeh ,
Po See Chen  and
Nan Tsing Chiu
Chieh Liang Huang
Affiliation:
Department of Psychiatry, China Medical University and Hospital, Taichung, Taiwan, ROC
Yen Kuang Yang*
Affiliation:
Department of Psychiatry, National Cheng Kung University Medical Center, 138, Sheng-Li Road, 704Tainan, Taiwan, ROC
Ching Lin Chu
Affiliation:
Department of Psychiatry, National Cheng Kung University Medical Center, 138, Sheng-Li Road, 704Tainan, Taiwan, ROC
I Hui Lee
Affiliation:
Department of Psychiatry, National Cheng Kung University Medical Center, 138, Sheng-Li Road, 704Tainan, Taiwan, ROC
Tzung Lieh Yeh
Affiliation:
Department of Psychiatry, National Cheng Kung University Medical Center, 138, Sheng-Li Road, 704Tainan, Taiwan, ROC
Po See Chen
Affiliation:
Department of Psychiatry, National Cheng Kung University Medical Center, 138, Sheng-Li Road, 704Tainan, Taiwan, ROC
Nan Tsing Chiu
Affiliation:
Department of Nuclear Medicine, National Cheng Kung University Medical Center, Tainan, Taiwan, ROC
*
*Corresponding author. Tel.: +886 6 276 6188; fax: +886 6 275 9259. E-mail address:ykyang@mail.ncku.edu.tw (Y.K.Yang).
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Abstract

The present study examined the relationship between the Lie scale scores and striatal D2/D3 receptor availability with respect to the cerebellum in 42 healthy community volunteers in Taiwan using single photon emission computed tomography (SPECT) with [123I]iodo-benzoaminde (IBZM). Even after controlling of age and educational level, subjects' Lie scale scores of the Maudsley personality inventory correlate negatively with D2/D3 receptor availability. Individual with higher Lie scale scores may have higher impulsivity due to lower dopaminergic availability.

Keywords

Striatal dopamine D2/D3 receptor availabilityPersonality inventorySocial desirability
Type
Short communication
Information
European Psychiatry , Volume 21 , Issue 1 , January 2006 , pp. 62 - 65
Copyright
Copyright © Elsevier SAS 2006

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References

Adams, SAMatthews, CEEbbeling, CBMoore, CGCunningham, JEFulton, J, et al.The effect of social desirability and social approval on self-reports of physical activity. Am. J. Epidemiol. 2005;161:389–398.CrossRefGoogle ScholarPubMed
Breier, AKestler, LAdler, CElman, IWiesenfeld, NMalhotra, A, et al.Dopamine D2 receptor density and personal detachment in healthy subjects. Am. J. Psychiatry 1998;155:1440–1442.CrossRefGoogle ScholarPubMed
Cloninger, CRSvrakic, DMPrzybeck, TRA psychobiological model of temperament and character. Arch. Gen. Psychiatry 1993;50:975–990.CrossRefGoogle ScholarPubMed
Dicken, CKSimulated patterns on the Edwards personal preference schedule. J. Appl. Psychol. 1959;43:372–377.CrossRefGoogle Scholar
Eysenck, HJEysenck, SBGManual of the Eysenck personality questionnaire. London: University of London; 1975.Google Scholar
Eysenck, SBGEysenck, HJAn experimental investigation of “desirability” response set in a personality questionnaire. Life Sci. 1963;2:343–355.CrossRefGoogle Scholar
Farde, LGustavsson, JPJonsson, ED2 dopamine receptors and personality traits. Nature 1997;385:590.CrossRefGoogle ScholarPubMed
Hill, SYZezza, NWipprecht, GLocke, JNeiswanger, KPersonality traits and dopamine receptors (D2 and D4): linkage studies in families of alcoholics. Am. J. Med. Genet. 1999;88:634–641.3.0.CO;2-M>CrossRefGoogle Scholar
Krause, KHDresel, SHKrause, Jla Fougere, CAckenheil, MThe dopamine transporter and neuroimaging in attention deficit hyperactivity disorder. Neurosci. Biobehav. Rev. 2003;27:605–613.CrossRefGoogle ScholarPubMed
Kumari, VEysenck personality inventory: impulsivity/neuroticism and social desirability response set. Psychol. Rep. 1996;78:35–40.CrossRefGoogle ScholarPubMed
Laruelle, MImaging synaptic neurotransmission with in vivo binding competition techniques: a critical review. J. Cereb. Blood Flow Metab. 2000;20:423–451.CrossRefGoogle Scholar
Lee, IHChen, CCYang, YKYeh, TLChen, PSChiu, NTCorrelation between striatal dopamine D2 receptor density and neuroticism in community volunteers. Psychiatry Res. Neuroimaging 2005;138:259–264.CrossRefGoogle ScholarPubMed
Lu, FHYang, YCWu, JSWu, CHChang, CJA population-based study of the prevalence and associated factors of diabetes mellitus in southern Taiwan. Diabetes Med. 1998;15:564–572.3.0.CO;2-H>CrossRefGoogle ScholarPubMed
Macaskill, GTHopper, JLWhite, VHill, DJGenetic and environmental variation in Eysenck personality questionnaire scales measured on Australian adolescent twins. Behav. Genet. 1994;24:481–491.CrossRefGoogle ScholarPubMed
Molto, JSegarra, PAvila, CImpulsivity and total response speed to a personality questionnaire. Pers. Individ. Dif. 1993;15:97–98.CrossRefGoogle Scholar
Moresco, FMDieci, MVita, AMessa, CGobbo, CGalli, Let al.In vivo serotonin 5HT(2A) receptor binding and personality traits in healthy subjects: a positron emission tomography study. Neuroimage 2002;17:1470–1478.CrossRefGoogle ScholarPubMed
Pliszka, SRRogeness, GAMedrano, MADBH, MHPG, and MAO in children with depressive, anxiety, and conduct disorders: relationship to diagnosis and symptom ratings. Psychiatry Res. 1988;24:35–44.CrossRefGoogle Scholar
Plomin, ROwen, MJMcGuffin, PThe genetic basis of complex human behaviors. Science 1944;264:1733–1739.CrossRefGoogle Scholar
Rosa-Neto, PLou, HCCumming, PPryds, OKarrebaek, HLunding, J, et al.Methylphenidate-evoked changes in striatal dopamine correlate with inattention and impulsivity in adolescents with attention deficit hyperactivity disorder. Neuroimage 2005;25:868–876.CrossRefGoogle ScholarPubMed
Schinka, JABusch, RMRobichaux-Keene, NA meta-analysis of the association between the serotonin transporter gene polymorphism (5-HTTLPR) and trait anxiety. Mol. Psychiatry 2004;9:197–202.CrossRefGoogle ScholarPubMed
Sheehan, DVLecrubier, YSheehan, KHAmorim, PJanavs, JWeiller, E, et al.The Mini-International Neuropsychiatric Interview (MINI): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J. Clin. Psychiatry 1998;59:22–33 (quiz 4-57).Google ScholarPubMed
Wacker, JReuter, MHennig, JStemmler, GSexually dimorphic link between dopamine D2 receptor gene and neuroticism-anxiety. Neuroreport 2005;16:611–614.CrossRefGoogle ScholarPubMed
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