Conversion of concept-specific decision confidence into integrative introspection in primates

Highlights

• Time-consuming compensatory process for metacognitive evidence operates in macaques

• The pIPL encodes the interaction of performance and confidence

• The pIPL integrates confidence specific for the concept of experience and novelty

• The pIPL prompts dorsal anterior cingulate cortex to output strategic actions

Summary

Introspection based on the integration of uncertain evidence is critical for acting upon abstract thinking and imagining future scenarios. However, it is unknown how confidence read-outs from multiple sources of different concepts are integrated, especially considering the relationships among the concepts. In this study, monkeys performed wagering based on an estimation of their performance in a preceding mnemonic decision. We found that the longer the response times for post-decision wagering, the more relieved the impairments having been caused by frontal disruption. This suggests the existence of a time-consuming compensatory metacognitive process. We found posterior inferior parietal lobe (pIPL) as its candidate, which was not coding the wagering per se (i.e., just high bet or low bet), but became more active when monkeys successfully chose the optimal bet option based on mnemonic decision performance. Thereafter, the pIPL prompts dorsal anterior cingulate cortex to carry the chosen wagering option. Our findings suggest a role for the pIPL in metacognitive concept integration.