Research paperImmunoglobulin G glycosylation in aging and diseases
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Abbreviations
ACPA
anti-citrullinated protein antibody
ADCC
antibody-dependent cell-mediated cytotoxicity
ANCA
anti-neutrophil cytoplasmic antibody
CDC
complement dependent cytotoxicity
CH2
constant heavy 2
Fab
fragment antigen binding
Fc
fragment crystallizable
FcγRs
Fcγ receptors
FNAIT
fetal and neonatal alloimmune thrombocytopenia
GlcNac
N-acetylglucosamine
HDFN
haemolytic disease of the fetus and newborn
HIV
human immunodeficiency virus
IBD
inflammatory bowel disease
IgG
immunoglobulin G
IVIg
intravenous immunoglobulin
MBL
mannose-binding lectin
NK
natural killer
RF
rheumatoid factor
SLE
systemic lupus erythematosus
Keywords
IgG glycome
Aging
Disease
Biological age
Differential glycosylation
Biomarker
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© 2018 The Author(s). Published by Elsevier Inc.