Cell
Volume 180, Issue 6, 19 March 2020, Pages 1037-1039
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Chemotherapy Induces Cancer-Fighting B Cells

https://doi.org/10.1016/j.cell.2020.02.046Get rights and content
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Tumor-infiltrating B cells are heterogeneous, and their roles in tumor immunity are controversial. In this issue of Cell, Lu and colleagues demonstrate that chemotherapy-induced complement signals promote the generation of ICOSL+B cells, which enhance tumor-specific T cell responses.

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