Original article
Clinicopathological trends of colorectal carcinoma patients in a tertiary cancer centre in Eastern India

https://doi.org/10.1016/j.cegh.2017.04.003Get rights and content
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Abstract

Background

The frequency of colorectal carcinoma is inadequate in India compared to the western world. The carcinoma of colon and rectum is usually disturbing among the individuals of older age group whereas it is less frequent in younger age group. This study was based on age, gender, site of primary tumor and histopathological type of colorectal cancer cases.

Methods

A retrospective study of 420 colorectal carcinoma cases admitted to Chittaranjan National Cancer Institute hospital, Kolkata, India during 2012–2016 was carried out. All the clinicopathological data was collected from the medical records of the patients. The detailed information was entered into tabular sheet and statistical analysis was performed.

Results

During these five years out of total cases in the Department of Surgical Oncology, 5.09% patients with colorectal carcinoma were admitted for colectomy or hemicolectomy. The percentage of younger age group (≤40 year) with colorectal cancer was rise up sharply in context of older age group (>60 year). The ratio of male and female affected in colorectal cancer was 1.6:1. Rectum was the most common site 46.2% among the total cancer lesions. From histopathological data, mucinous adenocarcinoma cases were identified with (23.6%) high frequency and mostly detected at younger age group (65.7%). It was found that 18.8% patients with synchronous liver metastasis and 16.7% of patients with Type 2 diabetes mellitus were likely to develop colorectal cancer.

Conclusion

The concise overview has documented an increased incidence of colorectal carcinoma patients amongst younger individuals with more aggressive forms like mucinous adenocarcinoma and also development of synchronous liver metastasis.

Keywords

Colorectal Cancer
Mucinous adenocarcinoma
Histopathology
Colectomy
Diabetes

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