Oral delivery of superoxide dismutase by lipid polymer hybrid nanoparticles for the treatment of ulcerative colitis
We report a membrane-penetrating peptide and PEG-modified lipid polymer hybrid nanoparticles that can orally deliver superoxide dismutase (SOD) for the treatment of ulcerative colitis.
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Declaration of competing interest
The authors declare no conflict of interest.
Acknowledgments
The authors acknowledge the financial support received form National Natural Science Foundation of China (No. 82073784), Jilin Province Science and Technology Development Program (No. 20200801012GH) and Industrial Technology Research and Development Projects from the Development and Reform Commission of Jilin Province (No. 2019C050-4). Meanwhile, the authors also acknowledge Key Laboratory of Pathobiology, Ministry of Education, Jilin University.
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