NoteStabilization of ribofuranose by a mineral surface
Graphical abstract
Section snippets
Experimental
Ribose was provided by Sigma. Aerosil 380 (SiO2) was provided by Evonik. It is a non-porous fumed silica with a BET surface area of 380 m2/g.
Results and discussion
TGA (thermogravimetric analysis) of bulk d-ribose shows an endothermic event without weight change at 90 °C, due to ribose melting,13 followed by four weight-loss events (195 °C, about 20%, endothermic; 280 °C, weakly exothermic, and 320 °C, strongly exothermic, 51%; and 510 °C, around 29%, strongly exothermic and resulting in complete combustion; Fig. 1 and SI-Fig. 1). Here we do not intend to discuss these events in detail but to use them as a fingerprint. The endothermic weight loss at the low
Conclusion
The major result of our work is the stabilization of the d-ribose on the surface of silica, under drying and even under basic conditions. The adsorption and the drying process also significantly increase the proportion of furanose forms compared to ribose in solution. A more complete study on the physical chemistry of adsorbed ribose is underway taking into account the influence of cation complexation, and the relation of furanose and more specifically the β-d-ribofuranose selection with the
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