ORIGINAL ARTICLEGLUT1-mediated effective anti-miRNA21 pompon for cancer therapy
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Graphical abstract
Preparation process, GLUT1-mediated transport and GSH-responsive drug release of DHA-targeting anti-miRNA21 nanopompons were reported. Nanopomponswere first obtained by rolling transformation transcription (RCT) and condensed by tumor-targteing pOEI-PEG-DHA.
KEY WORDS
MiRNA21
Dehydroascorbic acid
Rolling circle transcription
Self-assembly
RNAi nanoparticle
Tumor-targeting
Nanomedicine
Cancer treatment
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