Coronary Artery DiseaseUsefulness of the Baseline Syntax Score to Predict 3-Year Outcome After Complete Revascularization by Percutaneous Coronary Intervention
Section snippets
Methods
Extended description of study methods is presented in the online Supplementary Appendix.
The Efficacy of Xience/Promus Versus Cypher in Reducing Late Loss After Stenting (EXCELLENT) registry was a multicenter registry enrolling patients from 29 centers in Korea to compare the efficacy of everolimus-eluting stents (Xience/Promus) versus sirolimus-eluting stents (SES; Cypher) in all comers who underwent percutaneous coronary intervention (PCI) with unrestricted drug-eluting stent use.9 The study
Results
The all-comer EXCELLENT registry enrolled 5,159 patients, from which 71 patients (1.4%) had uninterpretable post-PCI angiographic images, leaving 5,088 patients (98.3%) with bSS and residual SS values. The SS was significantly reduced after PCI (13.6 ± 9.1 to 4.7 ± 6.5, p <0.05). CR was achieved in 2,173 patients (42.7%) and the bSS of these patients was 8.5 ± 6.3. Patients receiving CR were divided into approximate tertiles, according to bSS: 832 patients (38.3%) in low bSS (1 ≤ bSS < 6, mean:
Discussion
The present study investigated whether the bSS could predict future events in patients who achieved CR, which was defined as a residual SS = 0. To the best of our knowledge, this study is the first study to show evidence of the predictive value of the bSS in patients with CR. We found that although SS was reduced to 0 after PCI, the clinical outcomes were influenced by the bSS. The predictive value was applicable to not only target lesion-related outcomes but also to nontarget lesion-related
Disclosures
The authors have no conflicts of interest to disclose.
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2020, Asian Journal of SurgeryValidating the Performance of 5 Risk Scores for Major Adverse Cardiac Events in Patients Who Achieved Complete Revascularization After Percutaneous Coronary Intervention
2019, Canadian Journal of CardiologyCitation Excerpt :Additionally, in these patients, the performance of AS or MAS (both scores involve only 3 clinical variables) is unknown. In a previous study the authors attempted to examine whether SS and CSS could predict clinical outcomes in patients with CR and reported that these 2 scores were related to prognosis.25 The areas under the curve for SS and CSS with regard to 3-year MACE were 0.595 and 0.649, respectively.
SYNTAX Score and Pre- and Poststent Optical Coherence Tomography Findings in the Left Anterior Descending Coronary Artery in Patients With Stable Angina Pectoris
2017, American Journal of CardiologyCitation Excerpt :However, our study represents group of patients with stable angina who are not referred for coronary artery bypass grafting, thus have lower SS. It should also be noted that SS values in our study are consistent with those reported in the previous studies.5,26 Third, our analysis also included patients with single vessel disease.
Prognostic Value of the Clinical SYNTAX Score on 2-Year Outcomes in Patients With Acute Coronary Syndrome Who Underwent Percutaneous Coronary Intervention
2017, American Journal of CardiologyCitation Excerpt :Assessments of individual and population-based outcomes after PCI are extremely important in clinical practice. The SS is a scoring system based on the complexity and severity of coronary lesions and had been evaluated as an excellent prognostic tool for risk stratification in various clinical settings.5–7,14 Palmerini et al14 is the first to assess the SS for risk prediction in non–ST-segment elevation patients with ACS who underwent PCI and showed that the SS was a powerful independent predictor of adverse outcomes after PCI during 1-year follow-up.
Effect of Coronary Disease Characteristics on Prognostic Relevance of Residual Ischemia After Stent Implantation
2021, Frontiers in Cardiovascular Medicine
This study was supported by research grants from the Seoul National University Hospital (04-2012-0770 and 05-2016-0030).
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