Valvular Heart Disease
Comparison of Inhospital Outcomes of Surgical Aortic Valve Replacement in Hospitals With and Without Availability of a Transcatheter Aortic Valve Implantation Program (from a Nationally Representative Database)

https://doi.org/10.1016/j.amjcard.2015.07.039Get rights and content

We hypothesized that the availability of a transcatheter aortic valve implantation (TAVI) program in hospitals impacts the overall management of patients with aortic valve disease and hence may also improve postprocedural outcomes of conventional surgical aortic valve replacement (SAVR). The aim of the present study was to compare the inhospital outcomes of SAVR in centers with versus without availability of a TAVI program in an unrestricted large nationwide patient population >50 years of age. SAVRs performed on patients aged >50 years were identified from the Nationwide Inpatient Sample (NIS) for the years 2011 and 2012 using the International Classification of Diseases, Ninth Revision, Clinical Modification procedure codes. SAVR cases were divided into 2 categories: those performed at hospitals with a TAVI program (SAVR-TAVI) and those without (SAVR-non-TAVI). A total of 9,674 SAVR procedures were identified: 4,526 (46.79%) in the SAVR-TAVI group and 5,148 (53.21%) in SAVR-non-TAVI group. The mean age of the study population was 70.2 ± 0.1 years with majority (53%) of the patients aged >70 years. The mean Charlson's co-morbidity score for patients in SAVR-TAVI group was greater (greater percentage of patients were aged >80 years, had hypertension, congestive heart failure, renal failure, and peripheral arterial disease) than that of patients in SAVR-non-TAVI group (1.6 vs 1.4, p <0.001). The propensity score matching analysis showed a statistically significant lower inhospital mortality (1.25% vs 1.72%, p = 0.001) and complications rate (35.6% vs 37.3%, p = 0.004) in SAVR-TAVI group compared to SAVR-non-TAVI group. The mean length of hospital stay was similar in the 2 groups the cost of hospitalization was higher in the SAVR-TAVI group ($43,894 ± 483 vs $41,032 ± 473, p <0.0001). Having a TAVI program was a significant predictor of reduced mortality and complications rate after SAVR in multivariate analysis. In conclusion, this largest direct comparative analysis demonstrates that SAVRs performed in centers with a TAVI program are associated with significantly lower mortality and complications rates compared to those performed in centers without a TAVI program.

Section snippets

Methods

Data were obtained from the Nationwide Inpatient Sample (NIS) for the years 2011 and 2012. NIS is a part of a family of databases developed for the Healthcare Cost and Utilization Project (HCUP) and is sponsored by the Agency for Healthcare Research and Quality (AHRQ). Data from the NIS have previously been used to identify, track, and analyze national trends in health care usage, patterns of major procedures, access, disparity of care, trends in hospitalizations, charges, quality, and outcomes.

Results

A total of 9,674 SAVR procedures (which translates to an estimated 47,410 procedures performed in 1,110 hospitals) were identified of which 4,526 (46.79%) were performed in hospitals with availability of TAVI (SAVR-TAVI group) and 5,148 (53.21%) in non-TAVI hospitals (SAVR-non-TAVI group). Table 1 demonstrates the baseline characteristics of the study population. The mean age of the study population was 70.2 ± 0.1 years with majority (53%) of the patients aged >70 years; 58% were men and 78%

Discussion

In this analysis of patients aged >50 years who underwent SAVR in the United States, we demonstrate that inhospital mortality and complication rates of SAVRs performed in centers with a TAVI program is significantly less than those performed in centers without a TAVI program. Despite having greater burden of risk factors and co-morbidities, SAVRs performed in TAVI centers were associated with improved outcomes. This effect of TAVI on inhospital mortality and complication rates was also

Disclosures

None of the authors have anything to disclose.

References (22)

  • A. Deshmukh et al.

    In-hospital complications associated with catheter ablation of atrial fibrillation in the United States between 2000 and 2010: analysis of 93 801 procedures

    Circulation

    (2013)
  • Cited by (0)

    Drs. Singh, Badheka, and Patel share equal contribution to this manuscript.

    See page 1235 for disclosure information.

    View full text