Coronary Artery DiseaseOutcomes of Patients With Ischemic Mitral Regurgitation Undergoing Percutaneous Coronary Intervention
Section snippets
Material and Methods
All adults (>18 years) with severe (≥3+) IMR who underwent PCI at our institution from January 1, 1998, to January 1, 2010, were identified by querying our interventional cardiology databases. IMR was defined as functional MR in the presence of significant CAD. By definition, such patients had no evidence of structural or primary MV disease defined as rheumatic MV disease, myxomatous degeneration, endocarditis, MV prolapse, ruptured chordae, ruptured papillary muscles, or other structural MV
Results
All patients with severe IMR who underwent PCI from January 1, 1998, to January 1, 2010, at our institution were considered for inclusion. Those patients who did not have at least 1 echocardiogram before and after PCI at our institution were excluded. A total of 172 patients with severe IMR undergoing PCI and with available echocardiographic data were identified, of whom 35 were excluded because of MVRe, heart transplantation, or CRT-D implantation before PCI. Baseline clinical,
Discussion
Our study demonstrates that in patients with severe IMR and CAD, PCI alone improved IMR in approximately 1/3 of patients (36%), and in at least 3/4 of these patients, this improvement was sustained. Baseline LA size was the only predictor of improvement in severity of MR after PCI. There was evidence of LV reverse remodeling, and although the survival in patients with improvement in IMR was not statistically significant, it was numerically better.
MR in patients with CAD has been associated with
Disclosures
The authors have no conflicts of interest to disclose.
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