American Journal of Obstetrics and Gynecology
Original ResearchGynecologyReceipt of adjuvant endometrial cancer treatment according to race: an NRG Oncology/Gynecologic Oncology Group 210 Study
Section snippets
Materials and Methods
The NRG Oncology/GOG 210 Study was conducted from September 22, 2003, to December 1, 2011, at 62 US institutions. Eligible patients included women with presurgical diagnoses of EC or carcinosarcoma who were eligible for surgery and had not undergone previous retroperitoneal surgery or pelvic/abdominal radiation. Before surgery (hysterectomy, bilateral salpingo-oophorectomy, and lymph node sampling at the discretion of the treating provider), consenting patients completed a self-administered
Results
Of the 4898 study participants, 12% (n=615) self-reported black race. Table 1 shows distributions of epidemiologic characteristics according to race. Compared with white women with EC, black women with EC were more likely to have less than high school education, have lower annual incomes, be nonusers of menopausal hormones, be obese, have more live births, and have a history of diabetes mellitus. Distributions of tumor and treatment characteristics among black and white women with EC are shown
Comment
On the whole, studies that evaluate survival after a cancer diagnosis demonstrate lower survival rates among black women compared with white women.29 Morris et al30 describe several mechanisms that likely contribute to this observation: aggressive clinical characteristics, lower socioeconomic status, higher prevalence of comorbid conditions, poor patient-provider interactions, and inferior treatment. In this large cohort of women with EC, we examined the receipt of specific adjuvant treatments
Acknowledgments
The authors acknowledge the significant contributions of the late Dr D. Scott McMeekin who worked extensively on the GOG-210 study and Drs Wei Deng and Shamshad Ali for their contributions to the GOG-210 study.
The following institutions participated in this study: Roswell Park Cancer Institute, University of Alabama at Birmingham, Duke University Medical Center, Abington Memorial Hospital, Walter Reed Army Medical Center, Wayne State University, University of Minnesota Medical School,
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Cited by (0)
Supported by National Cancer Institute grants to the Gynecologic Oncology Group Administrative Office (CA 27469), the Gynecologic Oncology Group Statistical and Data Center (CA 37517) and the NRG Oncology Grant number: 1 U10 CA180822 and U10 CA180868. In addition, this research was supported in part by funds provided by the intramural research program of the National Cancer Institute, National Institutes of Health.
The authors report no conflict of interest.
Cite this article as: Felix AS, Cohn DE, Brasky TM, et al. Receipt of adjuvant endometrial cancer treatment according to race: an NRG Oncology/Gynecologic Oncology Group 210 Study. Am J Obstet Gynecol 2018;219:459.e1-11.