Original articleFundus Autofluorescence in Type 2 Idiopathic Macular Telangiectasia: Correlation with Optical Coherence Tomography and Microperimetry
Section snippets
Methods
The record of 12 patients with the diagnosis of type 2 IMT, seen at the National Eye Institute between 2003 and 2007, were reviewed retrospectively. The diagnosis in all cases was made based on typical fundus findings such as parafoveal graying or opacification of the retina, intraretinal crystalline deposits, and right-angled vessels, as well as the presence of parafoveal leakage on FA. Patients received complete ophthalmic examinations including best-corrected visual acuity (VA) testing using
Patient Population
Twelve patients (7 males and 5 females; mean age, 60 years) with findings of type 2 IMT in at least 1 eye were examined. One eye (Patient 8, right eye) was excluded from the series because of the presence of central maculopathy from central serous retinopathy as evidenced by the presence of pinpoint leakage on FA and subretinal fluid on OCT. Imaging data were unavailable for 1 eye (Patient 11, left eye) with advanced subretinal fibrosis resulting from neovascularization; this eye was not
Discussion
In this retrospective, cross-sectional case series, we used a multiple method approach to examine the ocular features of 12 patients with type 2 IMT. We observed on multiple modality examination that mild foveal increases in autofluorescence on FAF are detectable at a stage when other clinical or angiographic findings are not present (category 1). In eyes in which subtle and limited clinical and angiographic abnormalities first appear, this increase in central FAF signal becomes more prominent.
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