Original articleUveitis in Behçet disease: An analysis of 880 patients☆
Section snippets
Methods
We reviewed the medical records of 880 consecutive patients with ocular involvement of Behçet disease who visited the Uveitis and Immunology Service of the Ophthalmology Department, Istanbul University, Istanbul Faculty of Medicine, from 1980 to 1998. All patients were Turkish Caucasians. Only patients who met the 1990 classification criteria of the International Study Group for Behçet's Disease were included in the study.10 Patients who had ocular involvement other than uveitis were excluded.
Results
A total of 880 patients were included in the study. Mean age at presentation was 30 years (range, 9 to 71 years). Five hundred ninety-nine patients (68%) were male and 281 patients (32%) were female. Male-to-female ratio was 2.1:1. The total number of involved eyes was 1,567 (1,075 eyes in males and 492 eyes in females).
Extraocular clinical manifestations of Behçet disease are shown in Table 1. All patients had recurrent oral ulcers. The second most common extraocular clinical manifestation
Discussion
Uveitis in Behçet disease carries significant implications for the patient, because it is a chronic recurrent disease characterized by explosive attacks of severe inflammation that may cause significant damage to the intraocular structures. However, there are individual variations in disease course and severity, and several risk factors have been implicated to be associated with a severe course and a poor visual prognosis. Studies of large number of patients may help us improve our knowledge of
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