Chapter 12 - Proteomics of pressure ulcers in spinal cord injury

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Abstract

For proteomics researchers, it is challenging to predict how much the proteomic study of tissue, cells, and/or biological fluids will transform the diagnostic methods currently used in medicine. Alongside analytical techniques achieving enhanced sensitivity, our knowledge of the collateral effects of diseases will exponentially increase as well. Unquestionably, this development will bring greater diagnostic capacity at earlier stages and therefore, increasing survival rates. Furthermore, a deeper understanding of the pathophysiology of disease would allow us to develop a precision medicine based on each patient, optimizing the effectiveness of pharmacological treatments. It is essential to establish a solid basis in proteomics theory to achieve all their expected benefits.

To better understand pressure ulcers pathogenesis in spinal cord patients and to advance on new therapeutic options, proteomics offers substantial opportunities to to identify significant changes in protein during the course of pressure ulcers formation in an unbiased manner.

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