Chapter 6 - Polymeric micelles: a ray of hope among new drug delivery systems
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2022, Journal of Drug Delivery Science and TechnologyCitation Excerpt :A similar trend was observed for EE, except when the micelles were loaded with PTX. In this case, the percentage of EE decreased by 11.7% (from 88.9% to 77.2%) when the D/C ratio increased from 0.2 to 0.3, which can be explained by the limited solubilization capacity of the micelles [36,37]. These results suggested that CouPEG was an excellent carrier for PTX and CUR.
Hybrid nanostructures: Versatile systems for biomedical applications
2022, Coordination Chemistry ReviewsCitation Excerpt :For the transport of poorly water-soluble active drugs, polymeric micelles have been substantially investigated as a vehicle [60]. The Interior and exterior composition of polymeric micelles are made up of amphiphilic block copolymers [61], which in an aqueous solvent at a concentration above the critical micellar concentration (CMC) undergoes self-assembly into a micellar system [62]. The interior core of the micelles is made up of a hydrophobic block copolymer, which contains the hydrophobic drugs.
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