Chapter 9 - Cranberry Polyphenols: Effects on Cardiovascular Risk Factors

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Abstract

Cranberries are one of the most commonly consumed fruits rich in polyphenols, including but not limited to proanthocyanidins, anthocyanins, flavonols, and phenolic acids. These bioactive components not only have antioxidant capacity but also bring unique cardiovascular benefit to the human body. Despite of inconsistent findings in blood cholesterol, daily consumption of cranberry products tends to decrease oxidized low-density lipoprotein, which is considered to promote the risk of cardiovascular disease. Effect on vascular/endothelial function is emerging with some studies reporting improvement of flow-mediated blood vessel dilation, but data should be interpreted with caution. Evidence of cranberries’ effect on platelet aggregation, glucose, and insulin homeostasis is limited and inconsistent and may warrant future studies. In conclusion, scientific research suggests cranberries and cranberry products can be beneficial to heart health.

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