Clinical ScienceW. Bruce Jackson, MD, Section EditorEssential Fatty Acids in the Treatment of Dry Eye
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Cited by (64)
Associations between intake of dietary micro- and macro-nutrients with Dry eye syndrome: Blue Mountains Eye Study
2023, Clinical Nutrition ESPENNovel drug delivery systems for the management of dry eye
2022, Advanced Drug Delivery ReviewsCitation Excerpt :On the other hand, the major difference is that Diquas ophthalmic solution is a solution type, while Mucosta ophthalmic suspension UD2% is a suspension type, and some patients complain of temporary visual disturbances after Mucosta ophthalmic suspension UD2%, possibly because of the suspension type. Eicosanoids, which are derived from 20-carbon containing polyunsaturated fatty acids, act as local hormones [76] to reduce inflammation and alter the composition of myoblast lipids. Therefore, the oral administration of omega 3 fatty acids has been beneficial for DED patients [3,77].
Effects of a sea buckthorn oil spray emulsion on dry eye
2019, Contact Lens and Anterior EyeCitation Excerpt :These are precursors for eicosanoids, biologically active lipid mediators regulating inflammation. With the exception of dihomo-γ-linolenic acid (20:3n-6) derivatives, the n-6 fatty acid-derived eicosanoids are generally considered pro-inflammatory, whereas eicosanoids from n-3 fatty acids are anti-inflammatory or less inflammatory [20]. Very long-chain n-3 fatty acids are also precursors for resolvins and protectins, contributing to the resolution of inflammation [21].
Dry Eye Assessment and Management (DREAM©) Study: Study design and baseline characteristics
2018, Contemporary Clinical TrialsRelation Between Dietary Essential Fatty Acid Intake and Dry Eye Disease and Meibomian Gland Dysfunction in Postmenopausal Women
2018, American Journal of OphthalmologyCitation Excerpt :It is known that these 2 families of polyunsaturated fatty acids are inconvertible and distinct in their chemical structures, yet each of their respective intermediates competes for the same enzymes, resulting in products that often have antagonistic functions.10 Downstream n-3 products lead to an eicosanoid profile that is primarily anti-inflammatory, while downstream n-6 products often shift toward a proinflammatory milieu.10 Because of their shared enzymatic pathways, diets rich in n-6s tend to promote more inflammation, a core process in DED, and diets rich in n-3s tend to suppress inflammation.10
Sjogren's syndrome from the perspective of ophthalmology
2017, Clinical Immunology
Research supported in part by NEI EY 17626 and the Martin and Toni Sosnoff Fund.
The authors have no commercial or proprietary interest in any concept or product discussed in this article. Single-copy reprint requests to: Penny Asbell, MD (address below).
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Ms. Rosenberg will receive her MD degree in May 2010.