Chemistry & Biology
Volume 8, Issue 3, March 2001, Pages 289-299
Research PaperA small molecule designed to bind to the adenine nucleotide pocket of Hsp90 causes Her2 degradation and the growth arrest and differentiation of breast cancer cells
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Keywords
Her2
Hsp90 inhibitor
Novel anti-tumor agent
Geldanamycin
Abbreviations
GM
geldanamycin
RD
radicicol
17AAG
17-allylamino-17-demethoxygeldanamycin
MFGM
milk fat globule membrane protein
Rb
retinoblastoma protein
H&E
hematoxylin and eosin
TEA
triethylamine
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