Trends in Microbiology
ReviewRecent structural solutions for antibody neutralization of viruses
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Immunological factors that affect the in vivo fate of T7 phage in the mouse
2004, Journal of Virological MethodsEvolution of Cell Recognition by Viruses: A Source of Biological Novelty with Medical Implications
2003, Advances in Virus ResearchEvolution of foot-and-mouth disease virus
2003, Virus ResearchCitation Excerpt :Use of alternative receptors rendered the RGD dispensable, and a number of viable MAb-escape mutants with amino acid replacements at the RGD were characterized as variants with drastic antigenic alterations (Ruı́z-Jarabo et al., 1999, see Section 2.4, Fig. 4). These results with FMDV reinforce an early concept established with human influenza virus (review in Skehel and Wiley, 2000) that whenever surface amino acids are involved in both cell recognition and antibody binding, co-evolution of antigenicity and host cell tropism may take place, and this has recently been supported by studies with several viruses (Stewart and Nemerow, 1997; Baranowski et al., 2001a). Experimental inoculation of pigs with a clonal preparation of a FMDV type C (C-S8c1) resulted in the recovery of heterogeneous viral populations, as evidenced by the direct selection of monoclonal antibody resistant mutants (MARM) from viral populations present in lesions from infected animals (Carrillo et al., 1990).
Neutralizing antiviral antibody responses
2001, Advances in Immunology
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