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The Maudsley bipolar disorder project Clinical characteristics of bipolar disorder I in a Catchment area treatment sample

Published online by Cambridge University Press:  16 April 2020

Vanessa Raymont ,
David Bettany  and
Sophia Frangou
Vanessa Raymont
Affiliation:
Section of Neurobiology of Psychosis, P066, Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, LondonSE5 8AF, UK
David Bettany
Affiliation:
Section of Neurobiology of Psychosis, P066, Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, LondonSE5 8AF, UK
Sophia Frangou*
Affiliation:
Section of Neurobiology of Psychosis, P066, Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, LondonSE5 8AF, UK
*
*E-mail address: s.frangou@iop.kcl.ac.uk
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Abstract

The clinical characteristics of bipolar I disorder (BD1) have prognostic and therapeutic importance. The aim of this study was to examine the effect of demographic and clinical variables on the course of BD1. We reviewed the case notes of all BD1 patients (n = 63) receiving treatment in a London psychiatric service during a 1-month period. Depressive and manic onsets were equally likely without any gender difference. The earlier the age of onset, the more likely it was for patients to experience psychotic features. Only depressive onsets predicted a higher number of episodes of the same polarity. Male gender and substance abuse were associated with younger age at first presentation, while women with co-morbid substance abuse had more manic episodes. Male patients were more likely than females to be unemployed or single.

Keywords

Bipolar disorderCo-morbidityGenderClinical course
Type
Original article
Information
European Psychiatry , Volume 18 , Issue 1 , February 2003 , pp. 13 - 17
Copyright
Copyright © Éditions scientifiques et médicales Elsevier SAS 2003

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